Type 2 diabetes: Which medication is best?

Most Sort 2 diabetes drugs successfully lower glucose, however they work in various ways and have differing advantages and dangers. Picking the right medicine relies upon factors like weight, heart wellbeing, kidney capability, and expected secondary effects.

How Diabetes Drugs Work
1️⃣ Decrease Glucose Creation:

Metformin – Brings down glucose creation in the liver and further develops insulin awareness.
2️⃣ Increment Insulin Discharge:

Sulfonylureas (e.g., Glipizide, Glyburide) – Invigorate the pancreas to deliver more insulin (hazard of low glucose).
DPP-4 Inhibitors (e.g., Januvia, Tradjenta) – Assist with expanding insulin discharge after dinners.
3️⃣ Further develop Insulin Awareness:

Thiazolidinediones (e.g., Actos, Avandia) – Assist muscles with utilizing insulin all the more actually (hazard of weight gain and heart issues).
4️⃣ Lessen Sugar Retention in the Kidneys:

SGLT2 Inhibitors (e.g., Jardiance, Farxiga) – Assist with eliminating abundance sugar through pee; additionally heart-and kidney-defensive.
5️⃣ Copy Regular Stomach Chemicals (Incretins):

GLP-1 Receptor Agonists (e.g., Ozempic, Trulicity, Victoza) – Lower glucose, advance weight reduction, and safeguard the heart.
6️⃣ Direct Insulin Substitution:

Insulin Treatment – Utilized when different meds aren’t sufficient to control glucose.
Key Contemplations:
✅ Need to get in shape? → GLP-1 agonists or SGLT2 inhibitors
✅ Heart or kidney illness? → SGLT2 inhibitors or GLP-1 agonists
✅ Cost concerns? → Metformin or sulfonylureas
✅ Need to stay away from infusions? → Oral medications like Metformin, SGLT2 inhibitors, or DPP-4 inhibitors

The best medicine for Type 2 diabetes relies upon different elements, including your glucose levels, generally wellbeing, other ailments, and way of life. Here are a few normally endorsed prescriptions:

First-Line Treatment
✅ Metformin (Glucophage) – Generally usually suggested; assists lower with blooding sugar by lessening glucose creation in the liver and further developing insulin awareness.

Second-Line Choices (In the event that Metformin Alone Isn’t Sufficient)
💉 GLP-1 Receptor Agonists (e.g., Ozempic, Trulicity, Victoza) – Assists with weight reduction and brings down glucose; likewise heart-defensive.
💊 SGLT2 Inhibitors (e.g., Jardiance, Farxiga, Invokana) – Brings down glucose by assisting the kidneys with eliminating abundance glucose; additionally heart-and kidney-accommodating.
💊 DPP-4 Inhibitors (e.g., Januvia, Tradjenta) – Helps increment insulin delivery and lower glucose after dinners.
💊 Sulfonylureas (e.g., Glipizide, Glyburide, Glimepiride) – Animates insulin creation; can cause low glucose (hypoglycemia).
💊 Thiazolidinediones (TZDs) (e.g., Actos, Avandia) – Further develops insulin awareness however may have gambles with like weight gain or heart issues.

Insulin Treatment
In the event that oral drugs don’t control glucose really, insulin might be required, particularly in cutting edge cases.

Picking the Best One:
For weight reduction: GLP-1 receptor agonists or SGLT2 inhibitors
For heart/kidney benefits: SGLT2 inhibitors or GLP-1 receptor agonists
For cost-viability: Metformin or Sulfonylureas

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