Are antidepressants also pain relievers?

A few antidepressants can have torment easing properties, contingent upon their instrument of activity. While antidepressants are basically used to deal with mind-set issues like gloom and uneasiness, specific sorts are additionally recommended for overseeing ongoing agony conditions, in any event, when the patient isn’t encountering discouragement. This is how it’s done:

Sorts of Antidepressants Utilized for Help with discomfort:
1.Tricyclic Antidepressants (TCAs):

Models: Amitriptyline, Nortriptyline.
How they work for torment: These prescriptions influence synapses like serotonin and norepinephrine, which tweak torment signals in the focal sensory system.
Normal purposes: Neuropathic torment, fibromyalgia, headaches, and ongoing back torment.
2.Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs):

Models: Duloxetine (Cymbalta), Venlafaxine (Effexor).
How they work for torment: They increment serotonin and norepinephrine levels, which can improve torment restraint pathways.
Normal purposes: Neuropathic torment, fibromyalgia, osteoarthritis, and low back torment.
3.Specific Serotonin Reuptake Inhibitors (SSRIs):

Models: Fluoxetine (Prozac), Sertraline (Zoloft).
SSRIs are less successful for relief from discomfort than TCAs or SNRIs however may in any case help now and again, particularly when agony is connected to state of mind problems.
Why Are Antidepressants Utilized for Torment?
Constant agony frequently includes dysregulation of the sensory system, and antidepressants can tweak torment discernment pathways in the cerebrum and spinal rope.
They might upgrade the arrival of normal agony easing substances (like endorphins) and lessen the responsiveness of sensitive spots.
Conditions Treated with Antidepressants for Agony:


  • Neuropathic torment (e.g., diabetic
  • Neuropathy,
  • Postherpetic neuralgia)
  • Fibromyalgia
  • Ongoing low back torment
  • Headache anticipation


Strain cerebral pains
Significant Contemplations:
The aggravation letting impacts free from antidepressants for the most part happen at lower portions than those expected to treat sadness.
These prescriptions are not powerful for a wide range of torment, especially intense agony or agony because of injury.


Normal aftereffects incorporate tiredness, dry mouth, weight gain, or sickness, contingent upon the particular drug.
On the off chance that you’re thinking about antidepressants for torment, it’s fundamental to counsel a medical care supplier to decide the most fitting therapy for your particular condition.

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